May Cause Side Effects with Brooke Siem

May Cause Side Effects with Brooke Siem

155: Here’s what serotonin actually does in your body—and why that matters for antidepressant withdrawal.

Unpacking Part III of Chris Masterjohn, PhD's work on serotonin and SSRIs

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Brooke Siem
Aug 20, 2025
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In my last issue I introduced you to Chris Masterjohn, PhD, a nutritional scientist who has curiously wandered into the world of antidepressants and antidepressant withdrawal.

His work touches on a theory I have long suspected: antidepressant withdrawal isn’t so much about emotions generated by the brain as it is about a breakdown of systems in the body,…

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